Challenges at the Molecular Frontier

The molecular biology frontier.

To begin my personal reflection of Circulation Research, I would like to congratulate Eduardo Marbán and all the other Editors in commemoration of 50 years of this venerable journal. It is really a most honorable privilege for me to write this editorial, for Circulation Research was highly influential in encouraging me as a clinical cardiologist to become a scientific researcher. In 1970, I sta...

At the Frontier of Knowledge

At any time, there are areas of science where we are standing at the frontier of knowledge, and can wonder whether we have reached a fundamental limit to human understanding. What is ultimately possible in physics? I will argue here that it is ultimately impossible to answer this question. For this, I will first distinguish three different reasons why the possibility of progress is doubted and ...

Charge order at the frontier between the molecular and solid states in Ba3NaRu2O9.

We show that the valence electrons of Ba3NaRu2O9, which has a quasimolecular structure, completely crystallize below 210 K. Using an extended Hubbard model, we show that the charge ordering instability results from long-range Coulomb interactions. However, orbital ordering, metal-metal bonding, and formation of a partial spin gap enforce the magnitude of the charge separation. The striped charg...

Cosmic Rays at the Energy Frontier

New opportunities at the wild frontier

A better understanding of the natural history of model organisms will increase their value as model systems and also keep them at the forefront of research.